![]() ![]() Kaur K, Bhardwaj M, Kumar P, Singhal S, Singh T, Hooda S.Early separation of the placenta from the uterus wall.Hemorrhagic shock in an obstetric patient.Convulsion from the toxic reaction to local anesthetic drugs.Life-threatening hemorrhage due to disseminated intravascular coagulation (DIC).Phase 3 acute renal failure and acute respiratory distress syndrome (ARDS).Phase 2 coagulation disturbances of maternal hemostasis.Phase 1 respiratory and circulatory disorders.All of these occur during labor, cesarean delivery, dilatation, and evacuation, or within 30 min postpartum with no other explanation of findings.Coagulopathy or severe hemorrhage in the absence of other explanations.Four criteria must be present to make the diagnosis of AFE:.Cyanosis: ventilation-perfusion mismatching as a result of pulmonary vascular constriction.A rapid decline in pulse oximetry values or sudden absence or decrease in end-tidal carbon dioxide.Altered mental status, seizures, and coma. ![]() The maternal prognosis after amniotic fluid embolism is very poor.Any breach of the barrier between maternal blood and amniotic fluid forces the entry of amniotic fluid into the systemic circulation and results in a physical obstruction of the pulmonary circulation.During the second trimester of pregnancy.It is not a consequence of the “simple” mechanical respiratory obstruction, but a humoral effect causing anaphylactoid reactions or complement activation.Occurs when amniotic fluid, fetal cells, hair, or other debris enters the maternal pulmonary circulation and causes cardiovascular collapse.Amniotic fluid embolism (AFE) is one of the most catastrophic and life-threatening complications of pregnancy.blood clot dislodges and is swept into the pulmonary circulation and. Table of Contents Amniotic fluid embolism Learning objectives Amniotic fluid embolism (leakage to the blood from the placenta during delivery). ![]()
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